4 X Great
                               Grandparents
                                 /      \
                          3 X Great    4 X Great
                       Grandparents    Uncle-Aunt
                           /     \            \
                    2 X Great   3 X Great   1st Cousin
                  Grandparents  Uncle-Aunt  4 X Removed
                     /     \            \           \
               Great     2 X Great    1st Cousin   2nd Cousin
           Grandparents  Uncle-Aunt   3 X Removed  3 X Removed
               /     \           \            \           \
         Grand      Great       1st Cousin   2nd Cousin   3rd Cousin
        Parents   Uncle-Aunt    2 X Removed  2 X Removed  2 X Removed
         /     \           \            \           \           \
   Father     Uncle   1st Cousin    2nd Cousin    3rd Cousin    4th Cousin
   Mother     Aunt    Once Removed  Once Removed  Once Removed  Once Removed
   /     \           \           \            \           \           \
ME      Brother       1st          2nd         3rd         4th          5th
         Sister      Cousin       Cousin      Cousin      Cousin       Cousin
   \           \           \            \           \           \
    Son     Nephew   1st Cousin    2nd Cousin    3rd Cousin    4th Cousin
  Daughter   Niece   Once Removed  Once Removed  Once Removed  Once Removed
         \           \           \            \           \
         Grand      Great      1st Cousin  2nd Cousin  3rd Cousin
         Child  Nephew-Niece   2 X Removed  2 X Removed 2 X Removed
               \           \            \           \
              Great    2 X Great     1st Cousin  2nd Cousin
           Grandchild  Nephew-Niece  3 X Removed 3 X Removed
                     \           \            \
                  2 X Great  3 X Great      1st Cousin
                 Grandchild   Nephew-Niece  4 X Removed
                           \            \
                        3 X Great  4 X Great
                         Grandchild   Nephew-Niece
                                 \
                              4 X Great
                              Grandchild

Common usage allows the Great Aunt-Uncle and Great Nephew-Niece to be referred to as Grand Aunt-Uncle or Grand Nephew-Niece. Although an allowable usage, it is not the preferred usage.